enzyme	substrate	enzyme_genesymbol	substrate_genesymbol	residue_type	residue_offset	modification	sources	references
Q9Y385	Q92813	UBE2J1	DIO2	K	244	ubiquitination	SIGNOR	SIGNOR:29892818
Q9Y385	Q92813	UBE2J1	DIO2	K	237	ubiquitination	SIGNOR	SIGNOR:29892818
P38398	O75367	BRCA1	MACROH2A1	K	123	ubiquitination	SIGNOR	SIGNOR:28564596
P63279	O75030	UBE2I	MITF	K	308	ubiquitination	SIGNOR	SIGNOR:10673502
Q9UNE7	Q01860	STUB1	POU5F1	K	284	ubiquitination	SIGNOR	SIGNOR:29511337
P63208	Q13426	SKP1	XRCC4	K	296	ubiquitination	SIGNOR	SIGNOR:26774286
Q13616	Q13426	CUL1	XRCC4	K	296	ubiquitination	SIGNOR	SIGNOR:26774286
Q969H0	Q13426	FBXW7	XRCC4	K	296	ubiquitination	SIGNOR	SIGNOR:26774286
P63208	P35659	SKP1	DEK	K	137	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	344	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	84	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	349	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	57	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	331	ubiquitination	SIGNOR	SIGNOR:25278611
P63208	P35659	SKP1	DEK	K	284	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	137	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	344	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	84	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	349	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	57	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	331	ubiquitination	SIGNOR	SIGNOR:25278611
P62877	P35659	RBX1	DEK	K	284	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	137	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	344	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	84	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	349	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	57	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	331	ubiquitination	SIGNOR	SIGNOR:25278611
Q13618	P35659	CUL3	DEK	K	284	ubiquitination	SIGNOR	SIGNOR:25278611
Q8NHY2	Q53ET0	COP1	CRTC2	K	629	ubiquitination	SIGNOR	SIGNOR:17805301
Q8NHY2	Q53ET0	COP1	CRTC2	K	212	ubiquitination	SIGNOR	SIGNOR:17805301
Q13619	Q53ET0	CUL4A	CRTC2	K	629	ubiquitination	SIGNOR	SIGNOR:17805301
Q13619	Q53ET0	CUL4A	CRTC2	K	212	ubiquitination	SIGNOR	SIGNOR:17805301
P62877	Q53ET0	RBX1	CRTC2	K	629	ubiquitination	SIGNOR	SIGNOR:17805301
P62877	Q53ET0	RBX1	CRTC2	K	212	ubiquitination	SIGNOR	SIGNOR:17805301
Q16531	Q53ET0	DDB1	CRTC2	K	629	ubiquitination	SIGNOR	SIGNOR:17805301
Q16531	Q53ET0	DDB1	CRTC2	K	212	ubiquitination	SIGNOR	SIGNOR:17805301
Q7L5Y6	Q53ET0	DET1	CRTC2	K	629	ubiquitination	SIGNOR	SIGNOR:17805301
Q7L5Y6	Q53ET0	DET1	CRTC2	K	212	ubiquitination	SIGNOR	SIGNOR:17805301
P46934	O75896	NEDD4	TUSC2	K	71	ubiquitination	SIGNOR	SIGNOR:35167936
Q66K89	P04637	E4F1	TP53	K	321	ubiquitination	HPRD;SIGNOR	HPRD:17110336;SIGNOR:17110336
Q66K89	P04637	E4F1	TP53	K	319	ubiquitination	HPRD;SIGNOR	HPRD:17110336;SIGNOR:17110336
Q66K89	P04637	E4F1	TP53	K	320	ubiquitination	HPRD	HPRD:17110336
Q12933	Q13546	TRAF2	RIPK1	K	377	ubiquitination	SIGNOR	SIGNOR:18621737;SIGNOR:21232017;SIGNOR:8702708;SIGNOR:9712898
P55072	O95786	VCP	RIGI	K	181	ubiquitination	SIGNOR	SIGNOR:26471729
P63208	Q06609	SKP1	RAD51	K	58	ubiquitination	SIGNOR	SIGNOR:25585578
P63208	Q06609	SKP1	RAD51	K	64	ubiquitination	SIGNOR	SIGNOR:25585578
P62877	Q06609	RBX1	RAD51	K	58	ubiquitination	SIGNOR	SIGNOR:25585578
P62877	Q06609	RBX1	RAD51	K	64	ubiquitination	SIGNOR	SIGNOR:25585578
Q13616	Q06609	CUL1	RAD51	K	58	ubiquitination	SIGNOR	SIGNOR:25585578
Q13616	Q06609	CUL1	RAD51	K	64	ubiquitination	SIGNOR	SIGNOR:25585578
P14373	Q9Y2H1	TRIM27	STK38L	K	119	ubiquitination	SIGNOR	SIGNOR:35670107
P14373	Q9Y2H1	TRIM27	STK38L	K	73	ubiquitination	SIGNOR	SIGNOR:35670107
P63208	Q9H9Q4	SKP1	NHEJ1	T	181	ubiquitination	SIGNOR	SIGNOR:25661488
Q9Y297	Q9H9Q4	BTRC	NHEJ1	T	181	ubiquitination	SIGNOR	SIGNOR:25661488
Q13616	Q9H9Q4	CUL1	NHEJ1	T	181	ubiquitination	SIGNOR	SIGNOR:25661488
Q14258	O95786	TRIM25	RIGI	K	172	ubiquitination	SIGNOR	SIGNOR:24493797
Q6PJ69	Q9BYX4	TRIM65	IFIH1	K	743	ubiquitination	SIGNOR	SIGNOR:28031478
Q9Y4K3	O43474	TRAF6	KLF4	K	32	ubiquitination	SIGNOR	SIGNOR:31281496
Q9Y297	P10071	BTRC	GLI3	K	784	ubiquitination	SIGNOR	SIGNOR:17283082
Q9Y297	P10071	BTRC	GLI3	K	773	ubiquitination	SIGNOR	SIGNOR:17283082
Q9Y297	P10071	BTRC	GLI3	K	779	ubiquitination	SIGNOR	SIGNOR:17283082
Q9Y297	P10071	BTRC	GLI3	K	800	ubiquitination	SIGNOR	SIGNOR:17283082
Q13434	Q8IVH8	MKRN4P	MAP4K3	K	650	ubiquitination	SIGNOR	SIGNOR:34610951
Q9Y4K3	P04637	TRAF6	TP53	K	24	ubiquitination	SIGNOR	SIGNOR:27818144
Q13489	Q13546	BIRC3	RIPK1	K	377	ubiquitination	SIGNOR	SIGNOR:16603398;SIGNOR:18570872;SIGNOR:18621737
Q00987	Q13547	MDM2	HDAC1	K	74	ubiquitination	SIGNOR	SIGNOR:26832969
Q13191	P42226	CBLB	STAT6	K	398	ubiquitination	SIGNOR	SIGNOR:24508458
Q13191	P42226	CBLB	STAT6	K	108	ubiquitination	SIGNOR	SIGNOR:24508458
O60260	Q16665	PRKN	HIF1A	K	477	ubiquitination	SIGNOR	SIGNOR:29180628
Q9UJV3	Q96R06	MID2	SPAG5	K	409	ubiquitination	SIGNOR	SIGNOR:26748699
Q9BVG3	Q9H257	TRIM62	CARD9	K	125	ubiquitination	SIGNOR	SIGNOR:26488816
Q9UKB1	P25963	FBXW11	NFKBIA	K	22	ubiquitination	SIGNOR	SIGNOR:7479976;SIGNOR:9990853
Q9UKB1	P25963	FBXW11	NFKBIA	K	21	ubiquitination	SIGNOR	SIGNOR:7479976;SIGNOR:9990853
Q9NX47	O75460	MARCHF5	ERN1	K	481	ubiquitination	SIGNOR	SIGNOR:31368599
Q96AX9	Q13546	MIB2	RIPK1	K	377	ubiquitination	SIGNOR	SIGNOR:29642005
Q8IYU2	P63000	HACE1	RAC1	K	147	ubiquitination	SIGNOR	SIGNOR:23864022
O15033	Q9NR28	AREL1	DIABLO	K	62	ubiquitination	SIGNOR	SIGNOR:31732561
O15033	Q9NR28	AREL1	DIABLO	K	191	ubiquitination	SIGNOR	SIGNOR:31732561
P49459	P12004	UBE2A	PCNA	K	164	ubiquitination	SIGNOR	SIGNOR:12226657;SIGNOR:19706603
Q00987	Q9Y5A7	MDM2	NUB1	K	159	ubiquitination	SIGNOR	SIGNOR:28099510
Q9H992	Q15051	MARCHF7	IQCB1	K	48	ubiquitination	SIGNOR	SIGNOR:28498859
Q9UNE7	O00257	STUB1	CBX4	K	178	ubiquitination	SIGNOR	SIGNOR:32111827
Q9UNE7	O00257	STUB1	CBX4	K	280	ubiquitination	SIGNOR	SIGNOR:32111827
Q8NG06	O95786	TRIM58	RIGI	K	172	ubiquitination	SIGNOR	SIGNOR:23499489
Q9UHC7	P46783	MKRN1	RPS10	K	107	ubiquitination	SIGNOR	SIGNOR:31640799
Q12933	O43318	TRAF2	MAP3K7	K	158	ubiquitination	SIGNOR	SIGNOR:20038579
O60260	Q07812	PRKN	BAX	K	128	ubiquitination	SIGNOR	SIGNOR:28760928
Q9H6Y7	Q15836	RNF167	VAMP3	K	66	ubiquitination	SIGNOR	SIGNOR:23353890
Q9H6Y7	Q15836	RNF167	VAMP3	K	68	ubiquitination	SIGNOR	SIGNOR:23353890
Q9H6Y7	Q15836	RNF167	VAMP3	K	77	ubiquitination	SIGNOR	SIGNOR:23353890
Q9BYM8	Q49A26	RBCK1	GLYR1	K	505	ubiquitination	SIGNOR	SIGNOR:25278611
Q9BYM8	Q49A26	RBCK1	GLYR1	K	535	ubiquitination	SIGNOR	SIGNOR:25278611
Q9BYM8	Q49A26	RBCK1	GLYR1	K	338	ubiquitination	SIGNOR	SIGNOR:25278611
Q9BYM8	Q49A26	RBCK1	GLYR1	K	495	ubiquitination	SIGNOR	SIGNOR:25278611
Q96EP0	Q49A26	RNF31	GLYR1	K	505	ubiquitination	SIGNOR	SIGNOR:25278611
Q96EP0	Q49A26	RNF31	GLYR1	K	535	ubiquitination	SIGNOR	SIGNOR:25278611
Q96EP0	Q49A26	RNF31	GLYR1	K	338	ubiquitination	SIGNOR	SIGNOR:25278611
Q96EP0	Q49A26	RNF31	GLYR1	K	495	ubiquitination	SIGNOR	SIGNOR:25278611
P60604	Q92813	UBE2G2	DIO2	K	237	ubiquitination	SIGNOR	SIGNOR:29892818
P60604	Q92813	UBE2G2	DIO2	K	244	ubiquitination	SIGNOR	SIGNOR:29892818
O94874	P62805	UFL1	H4C14	K	32	ubiquitination	SIGNOR	SIGNOR:30886146
Q99942	Q7Z434	RNF5	MAVS	K	461	ubiquitination	SIGNOR	SIGNOR:20483786
Q99942	Q7Z434	RNF5	MAVS	K	362	ubiquitination	SIGNOR	SIGNOR:20483786
Q9Y4K3	P51617	TRAF6	IRAK1	K	180	ubiquitination	SIGNOR	SIGNOR:18347055
Q9Y4K3	P51617	TRAF6	IRAK1	K	134	ubiquitination	SIGNOR	SIGNOR:18347055
Q9H0M0	Q9Y2J4	WWP1	AMOTL2	K	347	ubiquitination	SIGNOR	SIGNOR:34404733
Q9H0M0	Q9Y2J4	WWP1	AMOTL2	K	408	ubiquitination	SIGNOR	SIGNOR:34404733
Q8IUD6	O95786	RNF135	RIGI	K	907	ubiquitination	SIGNOR	SIGNOR:19017631
Q8IUD6	O95786	RNF135	RIGI	K	909	ubiquitination	SIGNOR	SIGNOR:19017631
Q9H0X6	P08670	RNF208	VIM	K	97	ubiquitination	SIGNOR	SIGNOR:31862882
Q96J02	Q7Z434	ITCH	MAVS	K	420	ubiquitination	SIGNOR	SIGNOR:19881509
Q96J02	Q7Z434	ITCH	MAVS	K	371	ubiquitination	SIGNOR	SIGNOR:19881509
Q14258	Q969H0	TRIM25	FBXW7	K	412	ubiquitination	SIGNOR	SIGNOR:31186535
Q96JP5	P52597	ZFP91	HNRNPF	K	185	ubiquitination	SIGNOR	SIGNOR:29706618
Q969V5	Q86WV6	MUL1	STING1	K	224	ubiquitination	SIGNOR	SIGNOR:28763789
P14373	A8K0Z3	TRIM27	WASHC1	K	220	ubiquitination	SIGNOR	SIGNOR:23452853
P38398	O96028	BRCA1	NSD2	K	292	ubiquitination	SIGNOR	SIGNOR:32826945
Q00987	Q13761	MDM2	RUNX3	K	94	ubiquitination	SIGNOR	SIGNOR:19808967
Q9NS91	Q12888	RAD18	TP53BP1	K	1268	ubiquitination	SIGNOR	SIGNOR:19228710
Q8TBB1	Q9UMX1	LNX1	SUFU	K	470	ubiquitination	SIGNOR	SIGNOR:33608498
Q8TBB1	Q9UMX1	LNX1	SUFU	K	59	ubiquitination	SIGNOR	SIGNOR:33608498
Q8IUQ4	P67809	SIAH1	YBX1	K	304	ubiquitination	SIGNOR	SIGNOR:35273154
Q96PU5	O75385	NEDD4L	ULK1	K	933	ubiquitination	SIGNOR	SIGNOR:27932573
O60260	Q13501	PRKN	SQSTM1	K	13	ubiquitination	SIGNOR	SIGNOR:26746706
Q12899	Q14653	TRIM26	IRF3	K	87	ubiquitination	SIGNOR	SIGNOR:25763818
Q12899	Q14653	TRIM26	IRF3	K	70	ubiquitination	SIGNOR	SIGNOR:25763818
Q9NX47	O60260	MARCHF5	PRKN	K	220	ubiquitination	SIGNOR	SIGNOR:33565245
Q8IYW5	P16104	RNF168	H2AX	K	14	ubiquitination	SIGNOR	SIGNOR:22980979
Q99496	Q9C0C7	RNF2	AMBRA1	K	45	ubiquitination	SIGNOR	SIGNOR:24980959
Q68DV7	P12830	RNF43	CDH1	K	816	ubiquitination	SIGNOR	SIGNOR:31286874
Q9NS91	P12004	RAD18	PCNA	K	164	ubiquitination	SIGNOR	SIGNOR:20937699
Q9BUZ4	Q9HAU4	TRAF4	SMURF2	K	119	ubiquitination	SIGNOR	SIGNOR:31076633
O60260	P02788	PRKN	LTF	K	649	ubiquitination	SIGNOR	SIGNOR:32786404
Q969H0	P23769	FBXW7	GATA2	T	176	ubiquitination	SIGNOR	SIGNOR:25670854
O95198	Q9HA47	KLHL2	UCK1	K	81	ubiquitination	SIGNOR	SIGNOR:31938050
Q9HCE7	Q9P2Y5	SMURF1	UVRAG	K	517	ubiquitination	SIGNOR	SIGNOR:30686098
Q9HCE7	Q9P2Y5	SMURF1	UVRAG	K	559	ubiquitination	SIGNOR	SIGNOR:30686098
O60260	O43175	PRKN	PHGDH	K	330	ubiquitination	SIGNOR	SIGNOR:32478681
Q969V5	P31749	MUL1	AKT1	K	284	ubiquitination	SIGNOR	SIGNOR:22410793
P22681	O60674	CBL	JAK2	K	970	ubiquitination	SIGNOR	SIGNOR:28676638
P14373	O75385	TRIM27	ULK1	K	572	ubiquitination	SIGNOR	SIGNOR:35670107
P14373	O75385	TRIM27	ULK1	K	569	ubiquitination	SIGNOR	SIGNOR:35670107
Q8N653	P01116	LZTR1	KRAS	K	170	ubiquitination	SIGNOR	SIGNOR:30442762
Q9Y4K3	O43318	TRAF6	MAP3K7	K	34	ubiquitination	SIGNOR	SIGNOR:18758450
Q99942	Q86WV6	RNF5	STING1	K	150	ubiquitination	SIGNOR	SIGNOR:19285439
Q96PU5	P35240	NEDD4L	NF2	K	396	ubiquitination	SIGNOR	SIGNOR:33058421
Q9C0C9	O43541	UBE2O	SMAD6	K	173	ubiquitination	SIGNOR	SIGNOR:23455153
Q00987	P25098	MDM2	GRK2	K	19	ubiquitination	HPRD	HPRD:17006543
Q00987	P25098	MDM2	GRK2	K	21	ubiquitination	HPRD	HPRD:17006543
Q00987	P25098	MDM2	GRK2	K	30	ubiquitination	HPRD	HPRD:17006543
Q00987	P25098	MDM2	GRK2	K	31	ubiquitination	HPRD	HPRD:17006543
Q00987	P04637	MDM2	TP53	K	373	ubiquitination	HPRD	HPRD:11094089;HPRD:17110336
Q8N2H9	P51617	PELI3	IRAK1	K	134	ubiquitination	HPRD	HPRD:18326498
P46934	P51170	NEDD4	SCNN1G	K	10	ubiquitination	HPRD	HPRD:9351815
P46934	P51170	NEDD4	SCNN1G	K	12	ubiquitination	HPRD	HPRD:9351815
P46934	P51170	NEDD4	SCNN1G	K	13	ubiquitination	HPRD	HPRD:9351815
P46934	P51170	NEDD4	SCNN1G	K	26	ubiquitination	HPRD	HPRD:9351815
P46934	P51170	NEDD4	SCNN1G	K	6	ubiquitination	HPRD	HPRD:9351815
P46934	P51170	NEDD4	SCNN1G	K	8	ubiquitination	HPRD	HPRD:9351815
P40337	Q16665	VHL	HIF1A	K	532	ubiquitination	HPRD	HPRD:10944113
Q9H1A4	O95997	ANAPC1	PTTG1	K	9	ubiquitination	HPRD	HPRD:11179223
Q9NX47	Q9NX47	MARCHF5	MARCHF5	C	65	ubiquitination	HPRD	HPRD:16874301
Q9NX47	Q9NX47	MARCHF5	MARCHF5	C	68	ubiquitination	HPRD	HPRD:16874301