enzyme enzyme_genesymbol substrate substrate_genesymbol residue_type residue_offset modification sources references Q12933 TRAF2 Q13546 RIPK1 K 377 ubiquitination SIGNOR SIGNOR:8702708;SIGNOR:9712898;SIGNOR:18621737;SIGNOR:21232017 Q8IUD6 RNF135 O95786 RIGI K 907 ubiquitination SIGNOR SIGNOR:19017631 Q8IUD6 RNF135 O95786 RIGI K 909 ubiquitination SIGNOR SIGNOR:19017631 P60604 UBE2G2 Q92813 DIO2 K 237 ubiquitination SIGNOR SIGNOR:29892818 P60604 UBE2G2 Q92813 DIO2 K 244 ubiquitination SIGNOR SIGNOR:29892818 Q13489 BIRC3 Q13546 RIPK1 K 377 ubiquitination SIGNOR SIGNOR:16603398;SIGNOR:18570872;SIGNOR:18621737 Q96J02 ITCH Q7Z434 MAVS K 420 ubiquitination SIGNOR SIGNOR:19881509 Q96J02 ITCH Q7Z434 MAVS K 371 ubiquitination SIGNOR SIGNOR:19881509 Q66K89 E4F1 P04637 TP53 K 319 ubiquitination HPRD;SIGNOR SIGNOR:17110336;HPRD:17110336 Q66K89 E4F1 P04637 TP53 K 321 ubiquitination HPRD;SIGNOR SIGNOR:17110336;HPRD:17110336 Q66K89 E4F1 P04637 TP53 K 320 ubiquitination HPRD HPRD:17110336 Q12933 TRAF2 O43318 MAP3K7 K 158 ubiquitination SIGNOR SIGNOR:20038579 Q9C0C9 UBE2O O43541 SMAD6 K 173 ubiquitination SIGNOR SIGNOR:23455153 O15033 AREL1 Q9NR28 DIABLO K 191 ubiquitination SIGNOR SIGNOR:31732561 O15033 AREL1 Q9NR28 DIABLO K 62 ubiquitination SIGNOR SIGNOR:31732561 Q9Y4K3 TRAF6 O43318 MAP3K7 K 34 ubiquitination SIGNOR SIGNOR:18758450 Q9Y385 UBE2J1 Q92813 DIO2 K 244 ubiquitination SIGNOR SIGNOR:29892818 Q9Y385 UBE2J1 Q92813 DIO2 K 237 ubiquitination SIGNOR SIGNOR:29892818 Q9H0X6 RNF208 P08670 VIM K 97 ubiquitination SIGNOR SIGNOR:31862882 P14373 TRIM27 A8K0Z3 WASHC1 K 220 ubiquitination SIGNOR SIGNOR:23452853 Q9Y4K3 TRAF6 P51617 IRAK1 K 134 ubiquitination SIGNOR SIGNOR:18347055 Q9Y4K3 TRAF6 P51617 IRAK1 K 180 ubiquitination SIGNOR SIGNOR:18347055 Q99942 RNF5 Q86WV6 STING1 K 150 ubiquitination SIGNOR SIGNOR:19285439 Q8NG06 TRIM58 O95786 RIGI K 172 ubiquitination SIGNOR SIGNOR:23499489 Q9UKB1 FBXW11 P25963 NFKBIA K 21 ubiquitination SIGNOR SIGNOR:9990853;SIGNOR:7479976 Q9UKB1 FBXW11 P25963 NFKBIA K 22 ubiquitination SIGNOR SIGNOR:9990853;SIGNOR:7479976 Q969H0 FBXW7 P23769 GATA2 T 176 ubiquitination SIGNOR SIGNOR:25670854 P55072 VCP O95786 RIGI K 181 ubiquitination SIGNOR SIGNOR:26471729 P49459 UBE2A P12004 PCNA K 164 ubiquitination SIGNOR SIGNOR:19706603;SIGNOR:12226657 Q8NHY2 COP1 Q53ET0 CRTC2 K 629 ubiquitination SIGNOR SIGNOR:17805301 Q8NHY2 COP1 Q53ET0 CRTC2 K 212 ubiquitination SIGNOR SIGNOR:17805301 Q7L5Y6 DET1 Q53ET0 CRTC2 K 629 ubiquitination SIGNOR SIGNOR:17805301 Q7L5Y6 DET1 Q53ET0 CRTC2 K 212 ubiquitination SIGNOR SIGNOR:17805301 P62877 RBX1 Q53ET0 CRTC2 K 629 ubiquitination SIGNOR SIGNOR:17805301 P62877 RBX1 Q53ET0 CRTC2 K 212 ubiquitination SIGNOR SIGNOR:17805301 Q13619 CUL4A Q53ET0 CRTC2 K 629 ubiquitination SIGNOR SIGNOR:17805301 Q13619 CUL4A Q53ET0 CRTC2 K 212 ubiquitination SIGNOR SIGNOR:17805301 Q16531 DDB1 Q53ET0 CRTC2 K 629 ubiquitination SIGNOR SIGNOR:17805301 Q16531 DDB1 Q53ET0 CRTC2 K 212 ubiquitination SIGNOR SIGNOR:17805301 P63279 UBE2I O75030 MITF K 308 ubiquitination SIGNOR SIGNOR:10673502 Q9H0M0 WWP1 Q9Y2J4 AMOTL2 K 347 ubiquitination SIGNOR SIGNOR:34404733 Q9H0M0 WWP1 Q9Y2J4 AMOTL2 K 408 ubiquitination SIGNOR SIGNOR:34404733 Q99942 RNF5 Q7Z434 MAVS K 362 ubiquitination SIGNOR SIGNOR:20483786 Q99942 RNF5 Q7Z434 MAVS K 461 ubiquitination SIGNOR SIGNOR:20483786 Q9Y297 BTRC P10071 GLI3 K 784 ubiquitination SIGNOR SIGNOR:17283082 Q9Y297 BTRC P10071 GLI3 K 800 ubiquitination SIGNOR SIGNOR:17283082 Q9Y297 BTRC P10071 GLI3 K 779 ubiquitination SIGNOR SIGNOR:17283082 Q9Y297 BTRC P10071 GLI3 K 773 ubiquitination SIGNOR SIGNOR:17283082 Q8IYW5 RNF168 P16104 H2AX K 14 ubiquitination SIGNOR SIGNOR:22980979 Q969V5 MUL1 P31749 AKT1 K 284 ubiquitination SIGNOR SIGNOR:22410793 Q8N653 LZTR1 P01116 KRAS K 170 ubiquitination SIGNOR SIGNOR:30442762 Q96PU5 NEDD4L P35240 NF2 K 396 ubiquitination SIGNOR SIGNOR:33058421 O60260 PRKN O43175 PHGDH K 330 ubiquitination SIGNOR SIGNOR:32478681 O94874 UFL1 P62805 H4C8 K 32 ubiquitination SIGNOR SIGNOR:30886146 Q00987 MDM2 P25098 GRK2 K 19 ubiquitination HPRD HPRD:17006543 Q00987 MDM2 P25098 GRK2 K 21 ubiquitination HPRD HPRD:17006543 Q00987 MDM2 P25098 GRK2 K 30 ubiquitination HPRD HPRD:17006543 Q00987 MDM2 P25098 GRK2 K 31 ubiquitination HPRD HPRD:17006543 Q00987 MDM2 P04637 TP53 K 373 ubiquitination HPRD HPRD:11094089;HPRD:17110336 Q8N2H9 PELI3 P51617 IRAK1 K 134 ubiquitination HPRD HPRD:18326498 P46934 NEDD4 P51170 SCNN1G K 10 ubiquitination HPRD HPRD:9351815 P46934 NEDD4 P51170 SCNN1G K 12 ubiquitination HPRD HPRD:9351815 P46934 NEDD4 P51170 SCNN1G K 13 ubiquitination HPRD HPRD:9351815 P46934 NEDD4 P51170 SCNN1G K 26 ubiquitination HPRD HPRD:9351815 P46934 NEDD4 P51170 SCNN1G K 6 ubiquitination HPRD HPRD:9351815 P46934 NEDD4 P51170 SCNN1G K 8 ubiquitination HPRD HPRD:9351815 P40337 VHL Q16665 HIF1A K 532 ubiquitination HPRD HPRD:10944113 Q9H1A4 ANAPC1 O95997 PTTG1 K 9 ubiquitination HPRD HPRD:11179223